Vitamin B3 plays pivotal roles in cellular function and health, assisting with both DNA health and optimal energy metabolism via several important metabolic pathways.
In fact, many of the signs of aging, including the development of fatigue and cognitive difficulties, appear to be linked to the natural decline of this nutrient experienced in our golden years.
Nicotinamide riboside chloride (NRC) is a unique and very specific form of vitamin B3 that acts as a biological precursor to important coenzymes that maintain cellular health.
The conversion of NRC to these coenzymes is biologically straightforward, making it one of the most researched and talked about nutritional compounds for decades.
Is NRC for you?
Here are our top five reasons for seriously considering this powerful supplement:
1. Supporting Cellular Energy
NRC is a key player in maintaining and enhancing mitochondrial health and energy metabolism. The mitochondria are the energy powerhouses of the body, working tirelessly to generate cellular energy in the form of adenosine triphosphate (ATP). The experience of reduced energy and physical performance associated with ageing is intricately linked to reduced mitochondrial efficiency. By providing a bioavailable source of vitamin B3, like NRC, the mitochondria are nutritionally supported to continue producing energy optimally.
2. Longevity and Cellular Health
Long story short, we age because our cells age. There are several factors that cause cellular ageing – accumulated damage from oxidative stress and mitochondrial dysfunction being the most impactful. NRC has been shown to improve mitochondrial function at the same time as reducing oxidative stress, tackling two cellular problems at once. These benefits may result in improved tissue repair and cellular resilience, and have even been linked to small but significant increases in age spans in animal studies.
In addition, NRC has effects on the activity of a group of proteins – sirtuins – that have been linked to improved metabolic processes, stress resistance and longevity, meaning this nutrient can assist our cells in yet another way.
3. Improving Cognitive Function and Brain Health
As we’ve hinted at, mitochondrial efficiency is critical for virtually every process and system in the body, and the brain is no exception. It has been shown that age-related cognitive decline and neuroinflammation are directly linked to mitochondrial functions, which require ample nutrition. Animal studies have shown that supplementation with NRC significantly improves neuroplasticity and cognitive functions.
4. Sleep and Circadian Rhythm
Our sense of vitality and wellbeing are largely linked to our quality of sleep. As we age, stress, hormonal changes and fluctuations and altered circadian rhythms can all get in the way of a good night’s rest, in turn affecting our mood, energy and cognitive performance and clarity during the day. New evidence is emerging that links the circadian ‘clock’ – our sleep/wake cycle – with metabolic processes that require ample vitamin B3. Small human trials have shown that supplemented NRC helps to improve sleep efficiency and increase rapid eye movement (REM) sleep, the sleep phase important for memory consolidation, emotional processing and brain health.
5. Vitality and Wellbeing
In supporting cellular and mitochondrial function at a nutritional level, NRC also supports our experience of wellness and vitality. Some preclinical findings have looked at the impact of NRC on muscle health and while more trials are needed to confirm its action,
it appears that it may play a role in improving strength, stamina and performance.
Other studies suggest that in reducing markers of neuroinflammation, NRC may also help to lift and enhance mood.
No matter your age, in helping to restore cellular function and mitochondrial health, NRC is a promising nutrient that could serve you well into the future!
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